Shaggy and Scooby-Doo and friends must return 13 ghosts which they inadvertently released to a magical chest. Together with Daphne and Scrappy-Doo, along with newcomer Flim-Flam, they travel the world facing the ghosts that must be returned to the chest.
The gang lands their plane in a town populated by werewolves; Bogel and Weerd trick Scooby and Shaggy into opening the chest of demons; pint-sized conman Flim-Flam joins the gang.
The gang heads to the evil forest to capture Maldor the Magnificent, but their plan is botched and Daphne is put under a sleeping beauty spell.
The Chest of Demons is stolen by a shadow monster, so the gang heads off to maze-like Befuddle Manor to retrieve it, but soon they have to contend with demon chest escapee Queen Morbidia.
While visiting a Moroccan paranormal convention, the gang has to stop a mirror demon.
Horror host and demon chest escapee Zomba magically transports Scooby and the gang into the film "The Son of the Bride of the Ghost of Frankenstein."
Scooby and the gang plan a restful vacation, unaware that the cruise ship they've booked passage on is populated by ghosts.
Vincent Van Ghoul falls under a love spell cast by nefarious demon Nicara.
Scooby and the gang have to stop three bumbling witches who are in cahoots with demon Marcella.
Scooby has a traumatic experience with demon Time Slime and is replaced by lazy Bernie Gumshire, but Vincent Van Ghoul shows what will happen to the gang if Scooby doesn't come out of retirement.
Bogel and Weerd help demon Demondo imprison Scooby and the gang in the funny papers.
Vincent Van Ghoul is turned to stone; Scooby and the gang wind up in cahoots with Bogel and Weerd while fending off two overzealous security guards.
While visiting Scooby's parents in Dooville, Flim-Flam becomes hypnotized by a circus ringmaster.
While visiting a TV studio, the gang finds themselves swindled out of the Chest of Demons.