21 Jump Street revolves around a group of young cops who would use their youthful appearance to go undercover and solve crimes involving teenagers and young adults.
Hoffs and Garrett must deal with a DEA officer while working undercover at a massage parlor suspected of being a front for a drug operation.
Garrett attempts to infiltrate a high school drug ring by dating the sister of the ring's suspected leader.
McCann joins up to be the partner of a mentally handicapped youth in a school buddy system, to investigate the murder of the boy's former partner.
Doug falls for a narcotics officer with questionable tactics and a possible drug problem herself.
Hoffs is suspended from the force when while working undercover in high school she is forced to take a mandatory drug test and the results come back positive.
Doug has a strained reunion with his estranged younger brother Joey when Joey is assigned to the Jump St. team. Doug comes to his aid after Joey is brainwashed into joining a religious cult he was investigating.
Doug and Joey enroll in a wilderness camp for troubled teams to investigate a murder that happened there and find themselves constantly in trouble with the ex-marine who runs the place.
While investigating the hit and run murder of a high school football star, McCann becomes involved with a cheerleader who has AIDS.
Doug and Joey enroll in a college where good students are mysteriously being turned into criminals.
Doug is seriously wounded while on a case and while the doctors try to save his life he enters limbo where the people he meets there cause him to reconsider his choice of career.
After discovering that some white officers are responsible for beating and harassing black teenagers, Hoffs, with Fuller's help, try to convict them.
Hoffs, Joey and Mac help a raped girl that has no proof to convict the attacker.
Joey feels responsible for a baby girl he is taking care in a experimental program and try to find her drug addicted mother.
After finding the missing daughter of a famous reporter, Mac tries to solve the mistery behind the missing.
Mac has to date a daughter of a reputed drug dealer in a confidential FBI case at the same time he is trying to rebuild a relantionship with an old flame.
Mac and Joey try to find the responsibles for vandalizing elderly homes. The problem is that one of the prime suspects is the son of Fuller's girlfriend.
McCann infiltrates a group of devil worshipers whose leader has enthralled a teenage boy with her beauty.
Hoffs is charged in a civil suit for a man she has arrested for solicitation. At court, she has to confront the man and his representative, her boyfriend's vindictive ex-wife.
Mac goes undercover as a football player when a high school football star dies from an unexplained heart attack.
Fuller, Hoffs and Mac go undercover to investigate a gang of high school extortionists operating in a high school.
After seeing a teenager being murdered, Hoffs infiltrates the girl's street gang to find out who killed her.
Hoffs and Mac investigate a car theft ring near a high school, and the prime suspect is a pupil of Hoffs.