Dr. Joyce Reardon commissions a team of psychics to literally wake up a supposedly dormant haunted mansion—Rose Red.
A talented but eccentric parapsychologist hires a group of psychic mediums, including a teenage autistic savant with telekinesis, in order to wake up the horror in a century-old haunted house.
The team tours the mansion. Joyce and Steve point out that the home contains many optical illusions as well as an upside-down room and a library with a mirrored floor. Members of the team begin to disappear.
As Annie Wheaton falls and is knocked unconscious Rose Red's windows and doors mysteriously open again, prompting Emery to suggests that Annie be killed in order to allow everyone to escape the haunted house.