After many years spent at the “Cheers” bar, Frasier moves back home to Seattle to work as a radio psychiatrist after his policeman father gets shot in the hip on duty.
Roz's return to KACL rattles Frasier, who's reinvolved with Julia; Niles' fatherhood plans get an unexpected setback he determines to remedy with an unorthodox virility enhancer.
Love blinds Frasier to the faults of Julia, who behaves obnoxiously and insensitively at a Crane dinner gathering. For starters, she embarrasses Daphne, then winds up chattering incessantly on her cell phone.
Frasier and Niles suspect that Roz's new boyfriend, Barry, is gay. They see Barry on the street and believe that he has gone into a gay bar. Frasier, worried that Barry is leading Roz on, goes inside to confront him. Niles discovers that Barry actually went into an apartment building next door to the bar. He goes into the bar to tell Frasier, and a misunderstanding causes the patrons to believe the Crane brothers are actually lovers. A caller then "outs" Frasier on his show the next day. Martin feels very uncomfortable about the public thinking his son is gay. Alistair Burke, the head of the Seattle opera guild, befriends Frasier and begins spending a lot of time with him. The rest of the family realizes that Alistair thinks of Frasier as his boyfriend, but Frasier insists that this is not true. Frasier, Niles and Daphne attend a party, where Frasier discovers that everyone in attendance thinks that he and Alistair are a couple. Frasier is finally forced to come clean with Alistair about his sexuality after learning that Alistair expects to take their relationship to the next level very soon.
A courtship makes rivals of Martin and Frasier, who are vying for the affections of the latter's former baby-sitter, now a lounge singer with a vivacious personality and a quick wit that's appealing to both Crane senior and junior.
Roz tries to convince Frasier to go out with her friend Ann. She feels that Frasier is too particular about who he dates, and adds that there is nothing wrong with continuing to date around until the right person comes along. Frasier is reluctant, but soon grows tired of tagging along with Niles and Daphne and Martin and Ronee or hanging around the apartment alone. He agrees to a date with Ann, which proves to be a disaster. In the middle of the evening, he runs into Kenny, who is trying to persuade his beautiful and interesting cousin, Liz, to take a job in Seattle. Liz is leaving town the next day, so Frasier tries to ditch Ann so that he can spend time with her. Meanwhile, Niles and Daphne suspect that their maid is stealing from them.
Frasier overhears Ronee making a date with another man. He tells Martin, who is furious at him for eavesdropping. Ronee later breaks the news to Martin herself, explaining that she didn't think they had an exclusive relationship. He covers by claiming to be dating a woman named Sheila. Frasier gets stuck in the kitchen and overhears the conversation, and Martin accuses him of being a chronic eavesdropper. Martin runs into Ronee and her date at Cafe Nervosa, and tries to make her jealous by having Roz pose as the fictional Sheila. Frasier urges Martin to tell Ronee how he feels about her. Ronee comes over to talk to Martin, and Frasier leaves to give them some privacy. However, Roz inadvertently drives Ronee away, and Frasier somehow finds himself listening to another private conversation as Ronee and Martin sort things out in her car.
Niles receives a phone call from a panicked Maris, who asks to meet him for lunch. She asks for advice on how to handle her violent, philandering lover. Niles recommends that she leave him immediately. Frasier and Martin warn Niles not to tell Daphne about the lunch, as she is experiencing severe mood swings due to her pregnancy. Niles wants to tell Daphne anyway, but changes his mind after she freaks out about a phone call from Maris. Niles ends up having to pile lie upon lie to keep the news from Daphne, and even has to throw her a baby shower at the last minute after she suspects that is the reason for his odd behavior and nervousness. Maris's lover, Esteban, shows up at the shower in search of Niles. He mistakenly punches out Frasier as he tries to retaliate for Niles' advice. Daphne is furious to learn that Niles lied to her, and storms out. She later returns, and Niles promises that Maris will never come between them again. Just then, a radio report announces that Maris has been arrested for Esteban's murder. Meanwhile, Frasier reconsiders his decision to return to private practice after his first two days are marred by a series of disastrous (and short) sessions.
Niles is questioned by the police because he loaned Maris the murder weapon--an antique crossbow--for use in a play. Maris insists that she acted in self-defense. She continually calls Niles from jail, leaving Daphne extremely angry. The media scrutiny surrounding the Cranes intensifies after Frasier--the self-appointed family spokesman--accidentally says that Niles and Maris will be "executed" rather than "exonerated." Niles and Daphne have to come stay with Frasier, and Daphne makes Niles sleep on the couch. Frasier worries that Niles is reacting too calmly, as he believes that the anxiety will build up and eventually lead to a breakdown. Overcome with stress and sleep deprivation, Niles winds up stripping off all his clothes in Cafe Nervosa. Roz and Frasier manage to handle the situation. Niles finally begins to display some anger about his predicament, and asks Maris to back off and stop calling him so often.
Lilith comes to town for a one-day conference. She and Frasier try to get together, but keep having to cancel. Lilith discusses her romantic problems with a colleague at Cafe Nervosa before having to return to the conference. The woman then meets Frasier and arranges a blind date between an unwitting Frasier and Lilith. Frasier and Lilith plan to meet for drinks at her hotel before their date(s). When it takes longer than expected, Frasier calls the woman who arranged the date and says that he has to cancel. Lilith tries to save face by cancelling the date herself. She and Frasier each believe they have been stood up, but are hesitant to admit it to each other. They have a wonderful evening together, and even help the couple in the next room deal with relationship problems. Frasier winds up falling asleep and staying overnight. Meanwhile, a frantic Niles, Martin and Daphne try to undo the damage after Martin's gun accidentally discharges in Frasier's apartment.
Niles gains notoriety throughout Seattle because of his involvement in Maris's murder case. He and Daphne mingle with the city's social elite (including Bill Gates), and he is able to finagle reservations at booked restaurants. Frasier grows very jealous, but hopes that his two Sea Bee nominations (which break the record for most nominations in a career) will help him return to the spotlight. Kenny arranges for an interview, and Frasier invites the reporter to the ceremony. However, everything quickly begins to go wrong. Frasier loses his date because the event has to be scheduled for the morning due to Kenny's gaffe. He then loses both of the awards, and the attention of the reporter, who is much more interested in Niles. Roz, on the other hand, experiences the thrill of a lifetime when her judgmental sister--who has a seemingly perfect life--finally gets knocked off her pedestal.
Frasier is shocked when Frederick comes to visit sporting his new "goth" look. Meanwhile, realising that he never rebelled in his adolescance, Niles decides to try marijuana...with unexpected results.
Weight loss challenges KACL, enrolled in a pound-shedding contest that pits Frasier against a taunting nemesis who bullied him in high school.
Lawsuit fears plague Frasier over an accident in his kitchen that befell his insurer: a former date named Ann he snubbed. Now, Frasier entreats her to recuperate at his place, where Ann takes full advantage of the situation.
Strange dreams dominate this episode, which finds Frasier wed to Daphne, now a vociferous eater; Niles a carefree philanderer, dallying with bikini-clad repairwomen; and Martin a dashing hoofer, performing with Ronee.
Roz is disappointed when she is unable to get Alice tickets to a concert by children's performer Nanny G. After his family reveals that he used to be married to her, Frasier agrees to help Roz secure tickets. He accompanies Roz and Alice to a bookstore appearance, and continually drops hints to Nanny G about the fact that he is single.
A practical joke backfires, giving Martin a "mild cardiac event" that he's anxious to keep secret from Ronee, fearing that she'll think he's become "some feeble old guy."
Guilty feelings seize Frasier, who, just for a thrill, swipes a medallion from his neighbor, a chatty, trusting widow. Now he sets out to secretly return the object, with the reluctant help of Niles.
Lovelorn Frasier engages a matchmaker, who mismatches him with dinner dates that turn disastrous; well-meaning Niles hires a kooky helpmate for Daphne's delivery who works with a shaman--and a drummer.
Martin worries about a visit from Ronee's mother. She dislikes him because she once saw Martin innocently comforting the teenage Ronee and assumed he was trying to "take her virtue." Meanwhile, Frasier continues to find himself consumed by thoughts of Charlotte. Roz recommends that he get over it by going to a bar and picking up someone. Frasier quickly makes a connection with a woman named Kim, and they go back to his apartment.
Courting unnerves Frasier, whose wooing of a winsome matchmaker is constantly interrupted by her disarming beau, a dedicated environmentalist who's also quite cosmopolitan.
Country ways test Frasier and Charlotte, who're stranded at a farmhouse with a very odd family that has no idea who he is. Back home, a physical therapist is mistaken for a stripper in a situation that greatly embarrasses Niles.
As Frasier prepares for a dinner party, he considers throwing away an old broken crock pot. However, the crock pot stirs many memories of past experiences with his friends and family. Among the times he recalls are getting accidentally super-glued to a blind date after Martin tried to repair the pot; a birthday party for Roz that found Niles and Daphne feeling especially amorous.
Tumult on Martin's wedding day wreaks havoc with the elaborate fete.
Daphne's delivery highlights the conclusion of a two-parter that also resolves Frasier's dilemma with Charlotte and with his job at KACL.