Allison Dubois works in the District Attorney’s office using her natural intuition about people and her ability to communicate with the dead to help to solve crimes. Her dreams often give her clues to the whereabouts of missing people.
When they have the same dream about a missing homeless man who is the subject of Allison's most recent case, Bridgette and Allison swap personalities, causing mayhem at home, at school and with the investigation.
While investigating a rash of murders, Allison sees floating symbols above people's heads, signs that she thinks could match them with their perfect mate. Also, Joe is put in a tough situation when one of his employees accuses another of sexual harassment.
Scanlon is haunted by dreams of his late brother, leaving Allison concerned about her colleague. Also, while making her final preparations for college, Ariel has visions of missing young women, past and present.
While investigating a missing girl's murder, Allison experiences more friction with Scanlon after finding a possible link to his late brother. Also, Ariel deals with her siblings' reactions to her leaving for college.
When Allison gets a skin graft on her hand after a burn, she is puzzled when the same hand acts with a mind of its own, gesturing uncontrollably. Also, Bridgette keeps her real role on the soccer team a secret from her parents.
When Allison begins having flashes to a specific time in the future, her sense of dread grows as she feels more and more powerless to stop a catastrophic event from occurring.
Suddenly unable to understand the spoken word, Allison's marriage shows signs of strain and she develops an unexpected friendship with a linguist. Unable to communicate with his wife, Joe reaches the limits of his patience being married to a woman who is a slave to her visions.
A series of mysterious fire-related deaths may be tied to Allison's dreams of a blaze. Allison must also think about where her professional career is headed, as Devalos starts thinking seriously about running for mayor.
Allison's visions about the convicted sex offender new to her neighborhood have her questioning his guilt, even though her neighbors are furious about him moving in. Plus, Joe's potential career opportunity doesn't mesh with Allison's professional future.
Allison dreams of a murder that involves a man being struck by a train and, when a man is killed just like in her dream, Allison is convinced it's a homicide. Also, Joe has difficulty handling his mother's diagnosis.
Allison's dreams question her brother's recent good fortune; the Devalos campaign sees Bridgette as an asset.
A man wants Allison to help discover how his wife disappeared; Marie's breakdown in school causes concern for the Dubois parents.
When Allison becomes a lawyer and Joe starts a new job, the Dubois family is forever changed on the series finale of Medium.